白黎芦醇_____白黎芦醇；脂质体；包封率；正交设计

白黎芦醇脂质体的制备工艺改进

http://www.100md.com 《第四军医大学学报》 2005年第20期

白黎芦醇,,白黎芦醇；脂质体；包封率；正交设计,0引言,1材料和方法,2结果,3讨论,【参考文献】

     Study on preparation of resveratrol liposomes

    WANG Li, ZHOU Hong, ZHANG SanQi, GU Yi, FANG KunQuan, ZHOU Min, XI MiaoMiao, LIAN JiaFang

    1Department of Pharmacology, Faculty of Preclinical Medicine, Third Military Medical University, Chongqing 400038, 2Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xian 710033, China

    【Abstract】 AIM: To optimize the formulation and preparation techniques of resveratrol liposomes and to prepare them. METHODS: The resveratrol liposomes were prepared by filmultrasound technique. The optimal formulation and preparation techniques were selected by means of an orthogonal design test. The entrapment rate and appearance of liposomes were determined to evaluate the formulation and preparation technique. RESULTS: The appearance of prepared liposomes was regular and their size ranged from 80 to 100 nm. The entrapment rate of this kind of liposomes was 96.52% and its loading quantity was 19.81%. CONCLUSION: The selected formulation and preparation technique of resveratrol liposomes is rational and practicable. ......

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