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编号:10949816
血栓前体蛋白与同型半胱氨酸在血栓前状态中的价值
闁稿繑濞婇弫顓犳嫚瀹ュ繒绐�同型半胱氨酸,,血栓前状态;前体蛋白,血栓;同型半胱氨酸,0引言,1对象和方法,2结果,3讨论,【参考文献】

     Diagnostic value of thrombus precursor protein and homocysteine in prethrombotic state

    YANG XueMin ZHANG RunLing

    Clinical Laboratory, Second Hospital, Lanzhou University, Lanzhou 730030, China

    【Abstract】 AIM: To explore the diagnostic value of prethrombotic thrombus precursor protein (TpP) and homocysteine (tHcy) in patients with heart and brain diseases who are suspected of cardiac and cerebral embolism. METHODS: Plasma vWF, GMP140, tPA, PAI, TAT, TpP, DDimer and tHcy were measured by ELISA. Plasma PT, APTT and Fg were measured by autoinstrument ACL2000. RESULTS: Among the 60 patients under study, the plasma levels of vWF, GMP140, tPA, PAI, TAT, DDimer, TpP and tHcy in prethrombotic state with heart and brain diseases were significantly higher than those in controls (P﹤0.001). TpP and tHcy were more sensitive than other parameters. No significant difference was found in plasma PT, APTT and Fg before and after cardiac embolism and cerebral embolism (P>0.05). CONCLUSION: vWF, GMP140, tPA, PAI TAT, PAP, DDimer, TpP, tHcy are good biomarkers in assessing the prethrombotic state of patients with heart and brain diseases. High level of TpP and tHcy are helpful to predict the cardiac and cerebral embolism. ......

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   瀵邦喕淇婇弬鍥╃彿  閸忚櫕鏁為惂鐐  鐠囧嫯顔戦崙鐘插綖  閹兼粎鍌ㄩ弴鏉戭樋