血栓前体蛋白与同型半胱氨酸在血栓前状态中的价值
闁稿繑濞婇弫顓犳嫚瀹ュ繒绐�同型半胱氨酸,,血栓前状态;前体蛋白,血栓;同型半胱氨酸,0引言,1对象和方法,2结果,3讨论,【参考文献】
Diagnostic value of thrombus precursor protein and homocysteine in prethrombotic state
YANG XueMin ZHANG RunLing
Clinical Laboratory, Second Hospital, Lanzhou University, Lanzhou 730030, China
【Abstract】 AIM: To explore the diagnostic value of prethrombotic thrombus precursor protein (TpP) and homocysteine (tHcy) in patients with heart and brain diseases who are suspected of cardiac and cerebral embolism. METHODS: Plasma vWF, GMP140, tPA, PAI, TAT, TpP, DDimer and tHcy were measured by ELISA. Plasma PT, APTT and Fg were measured by autoinstrument ACL2000. RESULTS: Among the 60 patients under study, the plasma levels of vWF, GMP140, tPA, PAI, TAT, DDimer, TpP and tHcy in prethrombotic state with heart and brain diseases were significantly higher than those in controls (P﹤0.001). TpP and tHcy were more sensitive than other parameters. No significant difference was found in plasma PT, APTT and Fg before and after cardiac embolism and cerebral embolism (P>0.05). CONCLUSION: vWF, GMP140, tPA, PAI TAT, PAP, DDimer, TpP, tHcy are good biomarkers in assessing the prethrombotic state of patients with heart and brain diseases. High level of TpP and tHcy are helpful to predict the cardiac and cerebral embolism. ......
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