[摘要] 目的 探讨核素肾动态显像诊断糖尿病肾病(DN)的价值，为临床治疗和预后判断提供依据。方法 将25例糖尿病患者根据尿蛋白定性和定量结果分成无蛋白尿组10例和蛋白尿组15例，另选择健康者14例作为对照组。所有受试者均行核素肾动态显像，并同时测定血肌酐(Cr)、血尿素氮(BUN)、尿白蛋白(ALB)水平。结果 无蛋白尿组肾小球滤过率(GFR)及滤过分数(FF)高于对照组(P<0.05和P<0.01);蛋白尿组GFR及肾有效血浆流量(ERPF)明显低于对照组(P<0.01)，FF、血Cr、尿ALB高于对照组(P<0.01和P<0.05)。GFR、ERPF与病程、血Cr、BUN、尿ALB显著负相关(P<0.01和P<0.05)。结论 核素肾动态显像可早期诊断DN，并可了解肾功能的受损程度，为治疗方案的选择提供依据。

    [关键词] 糖尿病;放射性核素显像;肾功能

    Study of diabetes mellitus nephropathy diagnosed with radionuclide renal dynamic imaging

    LI Jian-gao，XU Yan-cheng

    (Zhongnan Hospital of Wuhan University，Wuhan430061，Hubei，China)

    Abstract:Objective It is to discuss the value of radionuclide renal dynamic imaging for diabetes mellitus nephropathy(DN)so as to provide reference for clinical treatment and prognosis predicting.Methods25patients with diabetes mellitus were divided into non-proteinuria group(10cases)and proteinuria group(36cases)according to the results of proteinuria qualitation and quantitation.14healthy people were chosen as control group.Radionuclide renal dynamic imaging was per-formed and the levels of blood creatinine(Cr) ......