【摘要】 目的 利用串联重复序列对我国的鼠疫菌株进行基因分型。 方法 对我国的165株鼠疫菌株的染色体DNA进行PCR扩增，然后利用UVIpro GAS7001X凝胶影像分析系统对扩增图谱进行长度分析。 结果 实验菌株都可以扩增出目的条带，按照其扩增片段长度分析可将实验菌株分为12个菌型。 结论 利用串联重复序列的长度多态性对我国的鼠疫菌株进行基因分型是一种切实可行的方法。

    【关键词】 鼠疫;重复序列;基因，分型

    Application of M28tandem repeat in genetype of the Y.pestis

    FU Xiu-ping，YU Dong-zheng，HAI Rong. Institute for Infectious Disease Control and Prevention of Chinese Center for Disease Control and Prevention，Beijing 102206，China

    【Abstract】 Objective To apply the M28tandem repeat to genetype the Y.pestis.Methods Chro-mosome DNA of the Chinese Y.Pestis was extracted and amplified by PCR and then the amplification fragment length was analyzed by UVIpro GAS7001X.Results Differences in diversity were observed among the selected isolates ......