【摘要】 目的 探讨肝炎、肝硬化患者血清CA125、CA199水平与肝损伤发生的关系。方法 慢性肝炎患者25例，肝硬化患者21例，正常对照组38例，测定血清CA125、CA199水平。结果 肝硬化患者血清CA125与CA199水平显著高于对照组，并随肝硬化程度加重而进行性增加；慢性肝炎患者血清CA125与CA199水平差异无显著性。结论 血清CA125与CA199水平在肝硬化患者中明显升高，且随肝硬化损害程度加重而升高，可作为反映肝硬化严重程度的一个无创伤性指标。

    【关键词】 肝硬化；肝炎；CA125；CA199

    【Abstract】 Objective To investigate the relation between the cirrhosis,hepatitis patient’s serum CA125,CA199 and the live damage.Methods Measure the CA125,CA199 lever by 25 cases hepatitis patient,21 cases cirrhosis patient,38 cases normal contrast group.Results The cirrhosis patient’s serum CA125,CA199 is higher than contrast group and aggravate with cirrhosis degree.There is no significant difference between the chronic hepatitis patient’s serum CA125 lever and CA199’s.Conclusion The cirrhosis patient’s serum CA125,CA199 obviously raise and aggravate with the cirrhosis damage degree,which can reflect the cirrhosis severity as a unwound’s index.

    【Key words】 cirrhosis;hepatitis; CA125 ; CA199

    CA125和CA199是高分子糖抗原 ......