【摘要】 目的探讨腹腔镜胃癌根治术对腹腔脱落癌细胞的影响。 方法收集44例行腹腔镜胃 癌根治术患者胃癌切除前后腹腔冲洗液，并以RT-PCR方法检测腹腔冲洗液CEA mRNA表达情况。 结果腹腔镜胃癌根治术患者CEA mRNA表达胃癌未切除时阳性率为27.3%(12/44)，切除后阳性率 为36.4%(16/44)，两组之间差异无统计学意义(P>0.05)。 结论腹腔镜胃癌根治术不增加腹腔胃 癌细胞的脱落。 【关键词】胃癌; 癌胚抗原; 腹腔镜; 根治性胃切除

    Changes of CEA mRNA in peritoneal lavage after laparoscopy-assisted radical gastrectomy and its clinical significanceQing Lian， Yu Peiwu， Wang Ziqiang， Luo Huaxing， Liu Wei. Department of GeneralSurgery， Southwest Hospital， Third Military Medical University， Chongqing 400038， China 【Abstract】 Objective To investigate the effect of laparoscopic-assisted radical gastrectomy on gas- tric cancer cells in peritoneal lavage fluid from patients' with gastric cancer. Methods Peritoneal lavagefluid from 44 patients with gastric cancer was collected before and after laparoscopic-assisted radical gas- trectomy to detect carcinoembryonic antigen (CEA) mRNA expression using RT-PCR. Results Thepre- ......