【摘要】 目的 了解儿童紫癜性肾炎(HSPN)的临床、病理类型，并初步探讨该病临床表现、病理类型与预后的关系。方法 总结1998年6月～2004年6月在我院住院，具有完整临床、病理资料的紫癜性肾炎患儿79例，其中72例随访观察1～6年，并就其临床病理类型及预后的关系进行回顾性分析。结果 临床表现以血尿和蛋白尿、单纯性血尿、肾病综合征最多，急进性肾炎最少。肾脏病理：表现为系膜增生、肾小球硬化、新月体形成，分级以Ⅱ级、Ⅲ级最多，Ⅱ级占73.3%。预后：临床痊愈占70.8%(51/72)，少数预后不良。结论 紫癜性肾炎病理改变以Ⅱ级、Ⅲ级为主。其预后与临床表现、病理分级密切相关。

    【关键词】 紫癜性肾炎；儿童；临床；病理

    Clinical pathological and prognosis in children with Henoch-Schonlein nephritis

    WANG Xu，LUAN Jiang-wei,YANG Xing-xian,et al.Wuhan Children Hospital,Wuhan 430016,China

    【Abstract】 Objective To analyze the clinical and pathological characteristic in children with Henoch-Schonlein nephritics(HSPN)，and to evaluate the associate factors of clinical outcome.Methods The clinical and pathological characteristics and the associated factors of clinical outcome were analyzed retropectively in 79 children with HSPN from June 1998 to June 2004 ......