前列腺癌组织PTI1基因mRNA的表达意义
前列腺肿瘤,,前列腺癌诱导基因1;逆转录聚合酶链反应;前列腺肿瘤;诊断,0引言,1对象和方法,2结果,3讨论
Expression and clinical significance of PTI1 in prostate cancer tissuesZHOU Yu1,WANG He1,QIN WeiJun1,ZHAO Jing2, SONG Bin1,ZHANG Geng1,ZHANG Bo1,YANG AnGang2
1Department of Urology,Xijing Hospital, 2Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fourth Military Medical University,Xian 710033,China
【Abstract】 AIM: To study the expression and clinical significance of PTI1 in prostate cancer tissues. METHODS: PTI1 was examined in 21 cases of prostate cancer tissues, 12 cases of benign prostatic hyperplasia (BPH) and 9 cases of normal prostate tissues by reverse transcriptionpolymerase chain raction (RTPCR). RESULTS: Specific bands of PTI1 were found in RTPCR products of 15 cases of prostate cancer tissues, but not in BPH and normal prostate tissues. CONCLUSION: Detection of PTI1 by RTPCR can be used in diagnosing prostate cancer. ......
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