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前列腺癌组织PTI1基因mRNA的表达意义
http://www.100md.com 《第四军医大学学报》 2005年第3期
前列腺肿瘤,,前列腺癌诱导基因1;逆转录聚合酶链反应;前列腺肿瘤;诊断,0引言,1对象和方法,2结果,3讨论
     Expression and clinical significance of PTI1 in prostate cancer tissues

    ZHOU Yu1,WANG He1,QIN WeiJun1,ZHAO Jing2, SONG Bin1,ZHANG Geng1,ZHANG Bo1,YANG AnGang2

    1Department of Urology,Xijing Hospital, 2Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fourth Military Medical University,Xian 710033,China

    【Abstract】 AIM: To study the expression and clinical significance of PTI1 in prostate cancer tissues. METHODS: PTI1 was examined in 21 cases of prostate cancer tissues, 12 cases of benign prostatic hyperplasia (BPH) and 9 cases of normal prostate tissues by reverse transcriptionpolymerase chain raction (RTPCR). RESULTS: Specific bands of PTI1 were found in RTPCR products of 15 cases of prostate cancer tissues, but not in BPH and normal prostate tissues. CONCLUSION: Detection of PTI1 by RTPCR can be used in diagnosing prostate cancer. ......

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