高血压_____]_缬沙坦；高血压；心室功能，左

缬沙坦对原发性高血压病人肥厚未逆转左心室整体舒张功能的影响

http://www.100md.com 《齐鲁医学杂志》 2006年第2期

高血压,,],缬沙坦；高血压；心室功能，左,1对象和方法,2结果,3讨论,[参考文献]

     [摘要] 目的评价缬沙坦改善原发性高血压病人肥厚未逆转左心室整体舒张功能的价值。方法选取口服缬沙坦6个月后，左心室肥厚未逆转的高血压病人32例，采用组织多普勒成像(TDI)技术测定二尖瓣环舒张早、晚期峰值运动速度(Em和Am)及其比值(Em/Am)，比较左心室肥厚未逆转病人口服缬沙坦6个月前后Em、Am以及Em/Am的变化。结果口服缬沙坦6个月后，Em明显增加(t=4.67，P<0.01)。结论缬沙坦能改善左心室肥厚未逆转的原发性高血压病人左心室整体舒张功能。

    [关键词] 缬沙坦；高血压；心室功能，左

    EFFECTS OF VALSARTAN ON LEFT VENTRICULAR DIASTOLIC FUNCTION IN PATIENTS WITH ESSENTIAL HYPERTENSION WITHOUT REVERSION OF LEFT VENTRICULAR HYPERTROPHY

    BI YIFANG, LIU YUJUN, JIN YANCHUN

    (Qingdao Sanatorium of Shandong Province, Qingdao 266071, China)

    [ABSTRACT]ObjectiveTo evaluate the effects of Valsartan on left ventricular diastolic function (LVDF) with essential hypertension without reversion of left ventricular hypertrophy. MethodsThirtytwo patients without reversion of left ventricular hypertrophy were selected to measure the early and late diastolic peak velocity of the mitral annulus (Em and Am) and the ratio (Em/Am) by Tissue Doppler Imaging (TDI). The parameters were compared before and after six months of treatment with oral Valsartan.ResultsThe early diastolic peak velocity of the mitral annulus (Em) increased obviously after sixmonth treatment with oral Valsartan (t=4.67, P<0.01).ConclusionValsartan can improve the left ventricular diastolic function in patients with essential hypertension without reversion of left ventricular hypertrophy. ......

百拇医药网 http://www.100md.com/html/DirDu/2006/04/12/96/53/97.htm

您现在查看是摘要页，全文长 6247 字符。