摘 要：目的：研究丽珠肠乐和氟西汀合用治疗腹泻型肠易激综合征(IBS)的临床疗效。方法：对54例腹泻型肠易激综合征病人随机分为治疗组30例和对照组24例，治疗组口服丽珠肠乐胶囊0.7g(2粒),每日2次，氟西汀胶囊10mg，每日2次，用8周。对照组口服丽珠肠乐胶囊0.7g，每日2次，用8周。结果:治疗组完全缓解14例(46.7%)，部分缓解12例(40%)，不缓解4例(13.3%)，总有效率为86.7%，对照组完全缓解4例(16.7%),部分缓解11例(45.8%)，不缓解9例(37.5%)，总有效率为62.5%，两组有明显差异(P<0.05)。结论:丽珠肠乐和氟西汀合用治疗腹泻型肠易激综合征疗效好，副作用少，尤其适用于伴有明显心理障碍的病人。

    关键词： 腹泻型肠易激综合征； 丽珠肠乐； 氟西汀

    Observe the Curative Effect of Livzon Bifidobacterium Preparation and Fluoxetine on Diarrehea-predominant Pattern Irritable Bowel Syndrome

    HUANG Zhi-hui

    (The People's Hospital of Huidong County, Guangdong Huidong 516300, China)

    Abstract：Objective：To investigate the curative effect of livzon bifidobacterium preparation and fluoxetine on irritable bowel syndrome.Methods：54 patients with diarrehea-predominant pattern irritable bowel syndrome were enrolled in this study.The patients were divided into two groups:30 patients in curative group and 24 patients in control group.The patient of curative group takes livzon bifidobacterium preparation capsule 0.7g,b.i.d,and fluoxetine capsule 10mg,b.i.d.for 8 weeks .The patient of control group takes livzon bifidobacterium preparation capsule 0.7g,b.i.d.for 8 weeks.Results： In the curative group 14 patients were complete remission(46.7%),12 patients were part remission(40%),4 patients were not remission(13.3%).The total effective rate are 86.7%.In the control group 4 patients were remission(16.7%),11 patients were part remission (45.8%),9 patients were not remission(37.5%).The total effective rate was 62.5%.The two groups have significant differences(p<0.05).Conclusion： The effect of Livzon bifidobacterium preparation and fluoxetine on diarrehea-predominant pattern irritable bowel syndrome is good.The two medicine have little side effect and especially for patients psychological block. ......