摘 要：目的：比较0.5% 耐乐品和0.5% 布比卡因对低位硬膜外麻醉的临床效果和安全性。方法：40例在硬膜外麻下施行下腹部手术的妇产科患者(ASAⅠ ～Ⅱ 级) 随机分为二组, 耐乐品组:05% 耐乐品(n= 20 例) ; 布比卡因组: 05% 布比卡因(n= 20 例)。取L 2～ 3行硬膜外穿刺, 注入首次剂量耐乐品或布比卡因8～10ml, 总量不超过20m l。观察两组病人用药总量、感觉阻滞范围和起效时间和副作用。结果：两组病人用药总量、感觉阻滞范围和起效时间无明显差异。耐乐品组止痛时间、肌松效果和感觉运动阻滞分离较布比卡因组强, 耐乐品组 低血压发生率较布必卡因高。结论：耐乐品组止痛时间、肌松效果和感觉运动阻滞分离较布比卡因组强。0.5% 耐乐品比0.5% 布比卡因在低位硬外麻中效果好。

    关键词： 布比卡因； 耐乐品； 麻 醉； 硬膜外

    Comparison between Naropin and Bupivacaine Used in Lower Level Epidural Obstruction

    WU Ting-ying, MO Jin-si, LUO Jian-gang

    (Yangjiang Western and Chinese Medicine Combination Hospital， Guangdong Yangjiang 529500, China)

    Abstract： Objective: To compare 0.5% Naropin with 0.5% Bupivacaine in clinical effect and safe for epidural anesthesia. Method: 40 cases of patients (ASA I – II grades) who are operated on lower abdomen under epidural anesthesia are divided into two groups; Naropin group: 0.5% Naropin (n = 20 cases); Bupivacaine group: 0.5% Bupivacaine (n = 20 cases). Taking L2～3 lines epidural puncture to be initially injected for Naropine or Bupivacaine 8～10 ml, gross dosage doesn’t exceed 20 ml. To observe two groups of patients who use gross medicine dosage, feeling obstruction scope, effect of initial taking medicine and side effect. Result: The difference between two groups using gross medicine dosage, feeling obstruction scope, effect of initial taking medicine is not clear; The Naropin group stopping pain time, muscle relaxing effect and feeling movement obstruction separation are relatively stronger than that of Bupivacaine group; The low blood pressure rate for Naropin is higher than that of Bupivacaine group. Conclusion: The 0.5% Naropin is better than 0.5% Bupivacaine in low level of epidural anesthesia. The Naropin group stopping pain time, muscle relaxing effect and feeling movement obstruction separation are relatively stronger than that of Bupivacaine group. ......