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胆红素与血清CK-MB关系的临床观察及分析
http://www.100md.com 《中华现代儿科学杂志》 2005年第12期
胆红素,,肌酸激酶同工酶;胆红素;新生儿,1资料与方法,2结果,3讨论
     【摘要】 目的 检测新生儿病理性黄疸时血清中肌酸激酶同工酶(CK-MB)的改变。方法 对病理性黄疸新生儿30例、生理性黄疸新生儿15例、正常新生儿10例于入院第2天测血胆红素浓度及CK-MB值。结果 生理性黄疸组和病理性黄疸组CK-MB值均增高,病理性黄疸组增高尤为明显,差异具有显著性。结论 高胆红素血症时存在胆红素对心肌的损伤,CK-MB可作为胆红素对心肌损伤的一个重要生化指标。

    【关键词】 肌酸激酶同工酶;胆红素;新生儿

    Observation and analysis of relationship between serum bilirubin and CK-MB

    HE Ping,LI Xue-qin.Department of Pediatrics,The Second Affiliated Hospital,Kunming Medical College,Kunming 650101,China

    【Abstract】 Objective To measure the changes of the serum CK-MBs concentration in neonates suffered from pathologic jaundice.Methods The serum bilirubin and CK-MB concentration in 30 neonates with pathologic jaundice,15 neonates with physiologic jaundice,10 normal neonates were examined on the second day in hospital.Results There was significant difference of serum CK-MBs concentration among three groups.The concentration of the CK-MB of pathologic jaundice group was espactially high than those of the other two groups(P<0.01).Conclusion There were damages to myocardium cells in neonates with hyperbilirubinemia and the concentration of the serum CK-MB can be used as a guideline to reflect the damages of myocardium cells. ......

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