奥曲肽联合特异性COX.2抑制剂对肝癌细胞的抑制作用
肝癌,,],NS.398;奥曲肽;肝癌;细胞增殖;凋亡,1材料与方法,2结果,3讨论,[参考文献]
Expression of substance P in intestinal tissue of rats and the relation between substance P and mucosa permeability in acute necrotizing pancreatitisSU Shi-zhi,SHI Xin,GAO Nai-rong
(1.Department of General Surgery,Daxing Hospital,Bejing102600,China;
2.Department of General Surgery,Zhongda Hospital,Southeast University,Nanjing210009,China)
Abstract:Objective To investigate the expression of substance P in rats'intestinal tissue and study the relation be-tween substance P and mucosa permeability in acute necrotizing pancreatitis(ANP).Methods 80adult Sprague-Dawley rats were randomly divided into control group(n=40)and ANP group(n=40).Sacrifices were made in8,12,16and20h later in every group after ANP model was established by injecting5%sodium taurocholate into pancreatic duct respectively.The in-testinal mucosal permeability and the expression of substance P were studied.Results In ANP groups,intestinal mucosal per-meability and the expression of substance P were significantly higher than those in the control group(P<0.05).The overex-pression of substance P was correlated with the intestinal mucosal permeability in ANP(r=0.66 ......
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