高血压伴肾上腺增生58例临床分析
高血压,,高血压；,肾上腺增生；,肾素；,血管紧张素；,醛固酮,1资料与方法,2结果,3讨论,参考文献:
摘要： 目的：探讨高血压伴肾上腺增生患者的临床特点。 方法： 对533例高血压患者进行肾上腺CT检查，根据CT显示肾上腺增生的高血压患者为试验组，共有58例，同时随机选取65例CT显示肾上腺正常的高血压患者为对照组，对2组患者的临床指标进行对比分析。结果：(1)在533例高血压患者中，伴肾上腺增生的有58例，占受检人群的10.88%。44例伴左侧肾上腺增生(75.86%)，14例伴双侧肾上腺增生(24.14%)。至今未发现伴右侧肾上腺增生的高血压病患者。(2)试验组血钾水平显著低于对照组，差异有统计学意义(P<0.05)。(3)2组卧立位血浆肾素活性、血管紧张素Ⅱ、醛固酮水平、血钠、24 h尿钾、尿钠水平及收缩压和舒张压差异均无统计学意义，但试验组的肾素活性、醛固酮水平、收缩压及舒张压水平均高于对照组。 结论：高血压伴肾上腺增生患者中肾上腺增生大部分为左侧肾上腺增生，其增生的肾上腺可能有自主分泌功能，影响血压的调节。关键词: 高血压； 肾上腺增生； 肾素； 血管紧张素； 醛固酮
The Clinical Analysis of Hypertension with Adrenal Hyperplasis in 58 patients
LUO Li, XU Xinjuan
(Department of Hypertension, First Affiliated Hospital，Xinjiang Medical University,Urumqi 830054, China)
Abstract: Objective: To observe the characters of hypertension with adrenal hyperplasis. Methods: 533 hypertensives all took the CT examination in adrenal. Based on the CT result, the patients were divided into hypertension with adrenal hyperplasis (n=58)and without adrenal hyperplasis (n=65). Results: (1) There were 58 hypertensives with adrenal hyperplasis in 533 patients including 44 in left adrenal (75.86%) and 14 in both adrenal (24.14%). We didn't find the patients with right adrenal hyperplasis. (2) The level of blood potassium in hypertension with adrenal hyperplasis was significantly lower than that in controls (P<0.05). (3) No significant difference was found between two groups in terms of plasma renin activity, angiotensin Ⅱ, aldosterone, blood sodium, 24 hours urine potassium and urine sodium, systolic and diastolic blood pressure. But the level of plasma renin activity, aldosterone, systolic and diastolic blood pressure was higher than in controls. Conclusion: It is suggested that hypertension with mostly occurred in left adrenal. Proliferated adrenal may produce autonomic excretion function and take part in the regulation of blood pressure. ......
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