Changes in vascular resistance index and the levels of NAG and ¦Â2ª²MG before and after high energy shockwaveª²induced renal damage

    Luo Xiaohui, Chen Xingfa, Sheng Binwu, Wang Xinyang, Zhou Xing, Ai Hong, He Dalin

    (Department of Urology, First Hospital, Medical School of Xi¬ðan Jiaotong University, Xi¬ðan 710061; B Ultrosound Room, First Hospital, Medical School of Xi¬ðan Jiaotong University, Xi¬ðan 710061, China)

    ABSTRACT: Objective To investigate the effect of resistance index by continuously ultrasonographic monitor and ¦Â2ª²MG, Nª²acetylª²¦Âª²Dª²glucosam in idase (NAG) in urine before and after ESWL in the renal damage caused by extracorporeal shock wave lithotripsy(ESWL). Methods A total of 40 rabbits were randomly divided into two groups: electromagnetic lithotripter group and electro hydraulic lithotripter group. Each group was divided into two sub groups: A group(1000) and B group(1500). RI and ¦Â2ª²MG, NAG were detected before and after ESWL in various time. Results 72 hours after ESWL, the level of RI, ¦Â2ª²MG and NAG increased obviously (P<0.01). The increase of data in group A were significantly lower than those in group B (P<0.01). The increase of data in the electromagnetic group were not significantly different from those in the electro hydraulic group(P>0.05). Conclusion RI, ¦Â2ª²MG and NAG might be effective makers to measure the renal damage by ESWL. Control of the number of ESWL impulse can lessen the damage of kidney. ......