抗病毒_____黄芩苷；盐酸小檗碱；提取工艺

芩连抗病毒胶囊提取方法研究

http://www.100md.com 《时珍国医国药》 2006年第1期

抗病毒,,黄芩苷；盐酸小檗碱；提取工艺,1仪器与试药,2醇提工艺考察及结果,3水提工艺考察及结果,4结果分析及讨论,参考文献：

     摘要：目的筛选芩连抗病毒胶囊醇提和水提最佳工艺。方法采用正交实验法对芩连抗病毒胶囊提取工艺进行考察，分别以组方中的黄芩苷和盐酸小檗碱的含量为指标进行测定。结果醇提工艺以10倍量70%的乙醇提取3次,1 h/次；水提工艺以10倍量水，煎煮2次，2 h/次所得到的黄芩苷和盐酸小檗碱的含量最高。结论此工艺对黄芩苷和盐酸小檗碱的提取率高，稳定性好，适合工业化生产。

    关键词：黄芩苷；盐酸小檗碱；提取工艺

    Study on Extraction Processes of Qinlian Antivirus Capsule

    CHEN Hongbao1, LIANG Shengwang2

    (1.Henan Zhongjing Sanitarian Medical Co.Ltd., Zhengzhou, Henan 450001, China; 2.Henan College of TCM, Zhengzhou,Henan 450008, China)

    Abstract:ObjectiveTo determine the optimum condition of extraction processes of Qinlian Antivirus Capsule.MethodsThe extraction processes were studied with the potentiametric method and the contents of baicalin and berberine hytrochloride as the markers.ResultsThe contents of baicalin and berberine hytrochloride were the highest when the following extraction condition was used:extracting with 70% alcohol and 10 times solvent for an hour a time and the process was repeated three times,and the extraction process of water is that 10 times solvent ,boiling twice ,2 hours per-time.ConclusionThe contents of baicalin and berberine hytrochloride are high and the stability is good when this extraction process is used. This extraction process is suitable for industrial production. ......

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