[摘要]目的 探讨血浆同型半胱氨酸(Hcy)在缺血性脑血管病发病过程中的临床意义以及与病情、伴发症的关系。 方法 采用化学发光法测定脑梗死患者血浆Hcy水平，并与正常对照组比较。 结果 脑梗死组血浆Hcy水平明显高于对照组(P<0.001);重型患者血浆Hcy水平明显高于中型及轻型患者(均为P<0.01);伴发高血压的患者血浆Hcy水平明显高于非高血压患者(P<0.05)。 结论 高Hcy血症是缺血性脑血管病新的重要危险因素;Hcy水平与病情密切相关。

    [关键词] 同型半胱氨酸;脑血管病;化学发光法

    Relationship between plasma homocysteine levels and ischemic cerebrovascular diseases

    ZHAO Yu-fang，JIANG Xiao-jin，JU Xing-dong，CHEN Rong

    (Department of Neurology，Qingdao Railway Hospital，Qingdao266002，China)

    Abstract:Objective To investigate the significance and effects of plasma homocysteine(Hcy)in oc-currence and development of ischemic cerebrovascular diseases and the relationship between plasma Hcy lev-els and condition of patients.Mothods The plasma Hcy levels were measured in patients with brain infarc-tion by automated chemiluminescence system，and compared with healthy controls.Results In the patient groups ......