【摘要】 目的：研究贝复剂(bFGF)对复发性口腔溃疡(ROU)的治疗效果。方法： 把138例轻型口腔溃疡患者随机分成两组，治疗组70例，用bFGF局部喷涂溃疡面；对照组68例，用0.2%洗必泰溶液喷涂溃疡面。结果：治疗组和对照组3天有效率分别为90.00%和61.76%，有显著性差异(P<0.05)；治疗组的溃疡平均愈合时间也显著少于对照组(P<0.05)。结论：bFGF对轻型口腔溃疡ROU具有显著疗效。

    【关键词 】 贝复剂；复发性口腔溃疡；碱性成纤维细胞生长因子

    The clinical effect of bFGF on recurrent oral ulcer

    SHANG Jun-lan, HAN Bing, SHI Ai-mei

    (Department of stomatology of the First Affiliated Hospital of Zhengzhou University, Henan 450052, China)

    【Abstract】 Objective：To study the effect of basic fibroblast growth factor (bFGF) on recurrent oral ulcer (ROU). Methods:138 Patients with ROU (minor aphthous ulcer) were divided into two groups randomly. The treated group including 70 patients was treated with bFGF spray, which was sprayed locally on the ulcer surface; the control group including 68 patients was treated with chlohexidine solution with the consistency of 0.2%.Results: In three days, the effective ratio of the treated group is 90.00%, while that of the control group is 61.76%, there is a statistically significant difference between those two groups (P<0.05); the average healing time of ulcer of the treated group is much shorter than that of the control group (P<0.05).Conclusions: bFGF could treat ROU effectively. ......