【摘要】 目的 观察参附注射液对手术后恶心呕吐(PONV)的预防效果，探讨中药预防与治疗术后恶心呕吐的可行性。方法 将60例经腹盆腔妇科手术患者，随机分为3组，每组20例(n=20)。参附组(S组)于手术开始前和手术结束前分别给予参附注射液20ml。恩丹西酮组(E组)于手术结束前给予恩丹西酮8mg。对照组(P组)手术结束前不另外给予止吐药物。3组病人均行经硬膜外术后镇痛，并于手术结束前经硬外管给予术后镇痛负荷剂量，分别在术后8h、24h、48h对病人作术后追踪观察并记录痛觉评分(采用视觉模拟评分法VAS)、恶心呕吐情况、使用止吐药的次数、腹部情况以及肛门排气时间等。结果 在恶心程度方面，E组与S组显著优于P组(P<0.01)，而S组患者腹部感觉舒适程度又比E组好(P<0.05)。P组术后呕吐发生率较E组和S组高(P<0.05)，S组患者肛门排气时间较P组和E组短(P<0.05)。结论 参附注射液用于预防PONV有较好的效果，有利于促进术后胃肠功能恢复。

    【关键词】 手术后恶心呕吐；参附注射液；镇痛

    Clinical application on the preventive and therapeutic effects of Shenfu Injection on postoperative nausea and vomiting

    SONG Li-dong,XIA Jie-hua.Department of Anesthesiology,Lijiang People's Hospital,Lijiang 674100,China

    【Abstract】 Objective To observe the preventive and therapeutic effects of Shenfu Injection on postoperative nausea and vomiting and explore a method of traditional Chinese medicine to prevent and treat postoperative nausea and vomiting(PONV).Methods Sixty patients undergoing elective gynecological surgery under spinal combined epidural anaesthesia were randomly divided into three groups(n=20).Patients in Group E were given endanstron 8mg at the end of the surgery ......