摘要: 随着交通、运输业和矿业的发展，急性脊髓损伤的发病率也不断上升。目前在临床治疗中普遍存在重视手术治疗(脊髓减压，脊柱稳定手术)，而忽视脊髓功能保护药物应用的趋势。其实，有相当一部分脊髓损伤的病人在早期并非完全性损伤，而是由于处理不当导致的继发性损伤造成的。因此，早期应用减轻水肿、对抗有害因子的药物和神经营养药物在保护脊髓功能中有着非常重要的作用。

    关键词: 脊髓损伤;药物治疗

    Pharmacological interventions for acute spinal cord injury

    JIANG Dian-ming

    (Department of Orthopaedics，First Affiliated Hospital of Chongqing University of Medical Sciences，Chongqing 400016，China)

    Abstract: The incidence of acute spinal cord injury(SCI)is ascending in the rising accidents of mining，construc-tion and transportation.When surgical decompression and stabilization gained widespread acceptance，the initial pharmaco-logical interventions which aim at neuroprotection are ignored.In patients with SCI，the primary or mechanical trauma sel-dom causes total transection，while the functional loss may be complete after secondary injury.Thus，pharmacological treat-ment which includes reducing edema，counteracting harmful consequences，and providing neurotrophic support in the early hours of the injury may play a critical role in neurological recovery following SCI.

    Key words:spinal cord injury;pharmacological intervention ......