Low dosage sufentanil used in conscious blind nasotracheal intubation

    LI Yuan, XU Liª²Xian, LU Lingª²Ling, ZHANG Guoª²Liang, MA Jiaª²Hai

    Department of Anesthesiology, Stomatological College, Fourth Military Medical University, Xi¬ðan 710033, China

    ¡¾Abstract¡¿ AIM: To investigate sedative and analgesic effect of little dosage sufentanil used in conscious blind nasotracheal intubation. METHODS: Sixty cases of maxillofacial surgery were selected and were randomly divided into 3 groups, with 20 cases in each group. The patients in group¢ñ were given fentanyl and midazolam by vein, the patients in group¢ò were given fentanyl and droperidol by vein, and the patients in group¢ó were only given sufentanil by muscular injection. Intramuscular premedication (Atropineª²Midazolam) was performed in all the cases. After surface anesthesia, conscious blind nasotracheal intubation was conducted. The changes of MAP, HR, SpO2, intubational complications, sedation score (Ramsay score), satisfaction and amnesia of patient in the three groups at T1 (before drug administration), T2 (after drug administration) and T3 (after the insertion of tracheal into tracheal) were observed. RESULTS: In group¢ñ and ¢ò, Compared with those at T1, the Ramsay score increased obviously at T2 and T3, and MAP, HR and SpO2 descended at T2, while MAP, HR and SpO2 rose significantly at T3 (P<0.05). In group¢ó, at T2 and T3, the patients were found in a mild degree of sedation, and no marked changes were observed in MAP and SpO, but HR descended obviously (P<0.05). No significant differences in the satisfaction and amnesia were found between the three groups (P>0.05). CONCLUSION: Low dose sulfentanyl can be applied to the sedation and analgesia in conscious blind nasotracheal intubation, which can lower cardiovascular adverse reactions. ......