Comparison between electrogastrogram and gastric emptying in patients with functional dyspepsia

    TANG Hongª²Wei1, LIU Li1, HUANG Yuª²Xin1, XU Haiª²Feng2, GAO Wei1, ZHOU Runª²Suo2, SHANG Lei3, GAO Feng2, AN Xiaoª²Li2

    1Department of Gastroenterology, 2Department of Nuclear Medicine, Tangdu Hospital, Xi¡¯an 710038, China, 3Department of Health Statistics, School of Preventive Medicine, Fourth Military Medical University, Xi¡¯an 710033, China

    ¡¾Abstract¡¿ AIM: To study the pathogenesis of functional dyspepsia (FD) by electrogastrogram and gastric emptying test. METHODS: According to the Rome¢òcriteria, patients with FD were classified into 3 subclasses. From each subclass, 10 patients were randomly chosen in this study. 10 Healthy volunteers were used as normal control. All the patients and volunteers underwent electrogastrogram examination and gastric emptying test. Gastric emptying test was performed using 99Tcmª²labelled solid food. Patients with FD were divided into 2 groups according to the results of gastric emptying test: normal gastric emptying group and delayed gastric emptying group. Data were collected accordingly and statistic analysis was performed. RESULTS: ¢Ù 18 patients showed gastric emptying delay. In patients with FD, postª²meal average amplitude (AP) and ¡÷AP reduced significantly (P<0.05), compared with the control. However preª²meal, postª² meal average frequency and preª²meal AP did not show significant changes(P>0.05); ¢ÚIn FD patients with normal gastric emptying, 41.7% showed abnormal electrogastrogram; ¢Û In the FD patients with delayed gastric emptying, 83.3% were abnormal in electrogastrogram and their postª²meal AP and ¡÷AP decreased significantly(P<0.05). However, preª²meal and postª² meal average frequency, preª²meal AP did not show significant changes(P>0.05). CONCLUSION: Motility disturbance of stomach plays an important role in the pathogenesis of FD. Electrogastrogram and gastric emptying test have a good consistency in determining FD. ......