肺挫伤研究现状及治疗
病理生理,,肺挫伤;胸部损伤;病理生理;机制;治疗,1肺挫伤的病理生理,2肺挫伤发生机制,3肺挫伤的影像学改变,4肺挫伤的治疗,5展望,参考文献:
摘要: 肺挫伤是主要的胸部钝性伤,严重肺挫伤死亡率较高,是胸部创伤的主要死亡原因之一。笔者收集了近几年有关肺挫伤基础研究及临床救治的文献报道,对肺挫伤后的病理生理、影像学研究及治疗进展作了重点介绍。关键词:肺挫伤;胸部损伤;病理生理;机制;治疗
Present study of pulmonary contusion and its treatment
XU Zhifei,LIU Junqiang
(Department of Thoracic and Cardiovascular Surgery,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China)
Abstract: Pulmonary contusion is a major injury in chest blunt injury with a high incidence.Severe pulmonary contusion has a high mortality and it is the major cause of death of chest trauma.In this article,the authors have reviewed the recent reports with a focus on the advances of its treatment,pathophysiologic change and image.
Key words:pulmonary contusion;chest injury;pathophysiologic;mechanism;treatment
肺挫伤(pulmonary contusion)是主要的胸部钝性伤,发生率在平时占胸部钝性伤的30%~70%,肺挫伤发生后,病情复杂,死亡率达10%~20%[1],如不及时有效地处理会发展成急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS),后果更为严重。
1 肺挫伤的病理生理
肺挫伤是一种实质细胞损伤。早期的病理改变主要是肺泡内出血、肺不张、水肿、实变和实质破坏,这些改变在早期是可逆的,在伤后12~24小时内呈进行性发展;如果病变不能有效控制,可进一步发展成ARDS[2]。
肺挫伤后的主要病理生理改变是肺的通气/血流失调引起组织缺氧 ......
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