丹参酮ⅡA对肝癌SMMC-7721细胞COX-2表达的影响
http://www.100md.com
徐俊丽, 和水祥, 陈静宏, 符 寒, 赵 刚,
丹参酮;环氧合酶-2;肝癌细胞;凋亡,徐俊丽,和水祥,符寒,赵刚,王艳丽,任牡丹,陈静宏,徐俊丽,通讯作者:,电话:,Q
 |
| 第1页 |
参见附件(1899KB，5页)。
徐俊丽, 和水祥, 符寒, 赵刚, 王艳丽, 任牡丹, 西安交通大学医学院第一附属医院消化内科 陕西省西安市 710061
陈静宏, 西安交通大学医学院病原微生物与寄生虫系 陕西省西安市 710061
徐俊丽, 西安交通大学医学院2004级硕士生, 主要从事慢性肝病的基础与临床研究.
陕西省中医局科研基金项目, No. 2001-040
通讯作者: 和水祥, 710061, 陕西省西安市雁塔西路277号, 西安交通大学医学院第一附属医院消化内科. hesx123@163.net
电话: 029-85322401 传真: 029-85323560
收稿日期: 2006-01-03 接受日期: 2006-03-29
Effect of tanshinone II A on COX-2 expression in hepatocellular carcinoma cell line SMMC-7721
Jun-Li Xu, Shui-Xiang He, Jing-Hong Chen, Han Fu, Gang Zhao, Yan-Li Wang, Mu-Dan Ren
Jun-Li Xu, Shui-Xiang He, Han Fu, Gang Zhao, Yan-Li Wang, Mu-Dan Ren, Department of Gastroenterology, the First Affiliated Hospital of Xi’an Jiaotong University Medical College, Xi’an 710061, Shaanxi Province, China
Jing-Hong Chen, Department of Microorganism and Parasitology, Xi’an Jiaotong University Medical College, Xi’an 710061, Shaanxi Province, China
Supported by Scientific Research Foundation of Shaanxi Traditional Chinese Medicine Office, No. 2001-040
Correspondence to: Dr. Shui-Xiang He, 710061, Department of Gastroenterology, the First Affiliated Hospital of Xi’an Jiaotong University Medical College, 277 Yanta West Road, Xi’an 710061, Shaanxi Province,China. hesx123@163.net
Received: 2006-01-03 Accepted: 2006-03-29
Abstract
AIM: To observe the effect of Tanshinone II A on the proliferation and apoptosis of human hepatocellular carcinoma cell line SMMC-7721 and its machanism.
METHODS: The human hepatocellular carcinoma cell line SMMC-7721 cultured in vitro was treated with different concentrations (final 0.5 mg/L) Tanshinone II A. The proliferation of the cells was measured by MTT assay, and the apoptosis of the cells was investigated by flow cytometry and transmission electron microscopy (TEM). The expression of Cyclooxygenase-2 (COX-2) was detected by immunocytochemistry ......
您现在查看是摘要介绍页，详见PDF附件(1899KB，5页)。