脑卒中急性期并发抑郁状态临床特点及治疗观察
脑卒中,,脑卒中；抑郁状态；百优解,1资料与方法,2结果,3讨论,参考文献
【关键词】 脑卒中；抑郁状态；百优解【摘 要】 目的 探讨脑卒中急性期并发抑郁状态的临床特点和治疗原则。方法 回顾分析88例脑卒中急性期并发抑郁状态患者的主要临床特点，并观察百优解治疗2周、4周时的疗效。结果 脑卒中急性期并发抑郁状态的发生率为26.0%(132/507)，其中多次卒中患者抑郁状态的发病率(46.9%) 明显高于首次发病的患者(21.0%)(P<0.01)。病灶主要位于左半球的例数是右半球的2.95倍(65/22)。位于半球前部的例数是后部的1.90倍(57/30)。入组的88例，轻度抑郁68例(77.3%)，中度抑郁14例(15.9%)，重度抑郁6例(6.8%)。百优解结合心理治疗2周时汉密尔顿抑郁量表(HAMD)评分较治疗前有显著下降(P<0.05)；4周时HAMD评分较2周时进一步下降(P<0.01)。结论 脑卒中急性期抑郁状态发生率较高，多次卒中患者更加明显，病灶多位于左半球及半球的前部。积极抗抑郁治疗不但能使抑郁症状得到很大地改善，而且能促进卒中后神经功能的恢复。
The clinical characteristics and observation of therapeutic effect in patients with cerebral stroke at acute period complicated with depression
QU Yifan,ZHOU Qin.
Suzhou Guangji Hospital,Suzhou 215008,China
【Abstract】 Objective To investigate the clinical features and treatment principles in patients with cerebral stroke at acute period complicated with depression.Methods The clinical manifestations and curative effect by Fluoxetine in 88 patients were retrospectively analyzed and summarized.Results The occurrence rate of cerebral stroke at acute period complicated with depression was 26.0% (132/507), the occurrence rate of multiple cerebral stroke was significantly higher than that of initial stroke (46.9% vs 21.0% P<0.01). The patients with left hemisphere lesions were 2.95 (65/22) times as many as those with right hemisphere lesion. The patients with the anterior lesions were 1.90 (57/30) times as many as those with the posterior lesions. Among 88 patients ......
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