MTHFR C677T基因多态性与新疆哈族和汉族食管癌易感性的关系

http://www.100md.com 张金芳, 庞丽娟, 赵 瑾, 陈湘川, 顾立怡,

亚甲基四氢叶酸还原酶;基因多态性;食管癌;哈萨克族;汉族,MTHFRC677T基因多态性与新疆哈族和汉族食管癌易感性的关系,张金芳,庞丽娟,赵瑾,陈湘川,李洪安,蒋金芳,梁伟华,赵娟,张丽翠,杨磊,李

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     张金芳, 庞丽娟, 赵瑾, 陈湘川, 李洪安, 蒋金芳, 梁伟华, 赵娟, 张丽翠, 杨磊, 李锋, 新疆地方病与民族高发病省部共建重点实验室, 石河子大学医学院病理教研室 新疆维吾尔族自治区石河子市 832002

    顾立怡, 葛春鸣, 项阳, 新疆伊犁州友谊医院、新华医院、农四师医院病理科 新疆维吾尔族自治区 835100

    张金芳, 2003级石河子大学硕士生, 主要从事肿瘤分子病理的研究.

    科技部重大基础研究前期研究专项, No. 2005CCA03700

    教育部科学技术研究重点项目, No. 206167

    2004年度石河子大学技术研究发展计划-重点项目, No. ZRKX2004-Z10

    通讯作者: 李锋, 832002, 新疆维吾尔族自治区, 石河子大学医学院病理教研室. lifeng7855@yahoo.com.cn

    电话: 0993-2057125 传真: 0993-2057136

    收稿日期: 2006-03-08 接受日期: 2006-03-24

    Association of methylenetetrahydrofolate reductase C677T polymorphism with susceptibility to esophageal cancer in Kazakh and Han populations in Xinjiang Uygur Autonomous Region

    Jin-Fang Zhang, Li-Juan Pang, Jin Zhao, Xiang-Chuan Chen, Li-Yi Gu, Chun-Ming Ge, Yang Xiang, Hong-An Li, Jin-Fang Jiang, Wei-Hua Liang, Juan Zhao, Li-Cui Zhang, Lei Yang, Feng Li

    Jin-Fang Zhang, Li-Juan Pang, Jin Zhao, Xiang-Chuan Chen, Hong-An Li, Jin-Fang Jiang, Wei-Hua Liang, Juan Zhao, Li-Cui Zhang, Lei Yang, Feng Li, Department of Pathology, Shihezi University School of Medicine, Shihezi 832002, Xinjiang Uygur Autonomous Region, China

    Li-Yi Gu, Chun-Ming Ge, Yang Xiang, Youyi Hospital; Xinhua Hospital; Nongsishi Hospital, Yili 835100, Xinjiang Uygur Autonomous Region, China

    Supported by the Special Foundation for Major Basic Research Program of the Ministry of Science and Technology, No. 2005CCA03700; the Scientific and Technological Research Key Program of Ministry of Education, No. 206167; and the Technology Research and Development Project of Shihezi University during 2004 period, No. ZRKX2004-Z10

    Correspondence to: Dr. Feng Li, Department of Pathology, Shihezi University School of Medicine, Shihezi 832002, Xinjiang Uygur Autonomous Region, China. lifeng7855@yahoo.com.cn

    Received: 2006-03-08 Accepted: 2006-03-24

    Abstract

    AIM: To investigate the gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T and its association with susceptibility to esophageal cancer (EC) in Kazakh and Han populations in Xinjiang Uygur Autonomous Region ......