长期质子泵抑制剂治疗老年反流性食管炎11例
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李 军, 吴本俨
反流性食管炎;老年人;质子泵抑制剂;长期,李军,吴本俨,通讯作者,Long-termuseofprotonpumpinhibitorsintreatment
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李军, 吴本俨, 解放军总医院南楼消化科 北京市 100853
通讯作者: 李军, 100853, 北京市, 解放军总医院南楼消化科. bjlijun1@sohu.com
电话: 010-66937512
收稿日期: 2006-05-09 接受日期: 2006-05-17
Long-term use of proton pump inhibitors in treatment of reflux esophagitis in 11 aged patients
Jun Li, Ben-Yan Wu
Jun Li, Ben-Yan Wu, Department of Gastroenterology, General Hospital of Chinese PLA, Beijing 100853, China
Correspondence to: Jun Li, Department of Gastroenterology, General Hospital of Chinese PLA, South Building, Beijing 100853, China. bjlijun1@sohu.com
Received: 2006-05-09 Accepted: 2006-05-17
Abstract
AIM: To observe the changes of symptoms in the aged patients with reflux esophagitis (RE) after long-term use of proton pump inhibitors (PPI).
METHODS: Eleven RE patients over 70 years old, who received PPI treatment for above 5 years, were investigated. The changes of reflux symptoms, the development of mucosal lesions under endoscope and the effects of PPI were analyzed.
RESULTS: Reflux symptoms were well controlled in all the 11 patients. Polypi (villous adenoma pathologically) were founded in duodenum in one case, who had been continuously treated with PPI for 6 years.
CONCLUSION: Long-term use of PPI is benefit for the aged RE patients in the control of the symptoms, but it is necessary to pay attention to the occurrence of digestive cancer.
Key Words: Reflux esophagitis; Aged patients; Proton pump inhibitors; Long-term use
Li J, Wu BY ......
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