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加味黄芪参麦五苓汤治疗扩张型心肌病并心衰的作用研究
http://www.100md.com 《广东药学院学报》 2005年第3期
扩张型心肌病,,加味黄芪参麦五苓汤;扩张型心肌病;心力衰竭;心功能,1资料与方法,2结果,3讨论,参考文献:
     摘要:目的 观察加味黄芪参麦五苓汤对扩张型心肌病并心力衰竭(心衰)的治疗作用。方法 扩张型心肌病并心力衰竭患者60例,随机分为对照组和治疗组,对照组进行西医常规治疗,治疗组同时加服加味黄芪参麦五苓汤。治疗前、后对心功能进行评定。结果 治疗后治疗组的临床症状改善更明显,平均左心室射血分数(LVEF)为(61.5±7.2)%,较对照组的(47.2±66)%明显好转(P<0.05)。治疗组的有效率83.3%,对照组的有效率56.7%,差异有显著性(P<0.05)。结论 加味黄芪参麦五苓汤联合西药治疗扩张型心肌病并心衰较西医常规治疗更能改善心脏功能和症状,延缓病情的进展。

    关键词:加味黄芪参麦五苓汤;扩张型心肌病;心力衰竭;心功能

    Study of HuangqiShenmaiWuling decoction on the treatment of dilated cardiomyopathy complicated with heart failure

    LIANG Biwei

    (Institute of Cardiovascular Diseases of Guangdong Province, Guangzhou 510080,China)

    Abstract: Objective To study the efficacy of HuangqiShenmaiWuling decoction on dilated cardiomyopathy complicated with heart failure. Methods 60 patients diagnosed of dilated myocardial disease complicated with heart failure were randomized into treatment group and control group. Control group was administered with standard western medical therapy; treatment group was administered with both HuangqiShenmaiWuling decoction and western medicine. And the variations of heart functions before and after therapy in each patient were campared. Results No significant difference was observed in heart functions before treatment in the two groups(P>0.05). After therapeutic traetment, patients in treatment group had more relief in symptoms, higher left ventricular ejection fractions (LVEF) (61.5±7.2% vs 47.2±6.6%, P<0.05), and higher rate of effectiveness (83.3% vs 56.7%, P<0.05) than the control group. Conclusion Compared with those treated with ordinary western medicines, patients administered with both HuangqiShenmaiWuling decoction and western medicine have greater improvement on heart function, what may slow down the progress of the disease ......

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