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编号:10980048
马龙县孕妇麻疹抗体水平及婴儿麻疹疫苗免疫效果分析
http://www.100md.com 《中华医学研究杂志》 2006年第4期
麻疹疫苗,,妊娠;婴儿;麻疹疫苗;接种;抗体,1对象与方法,2结果,3讨论,【参考文献】
     【摘要】 目的 了解孕妇麻疹免疫状况和婴儿麻疹疫苗免疫效果。方法 对112名孕妇产前和50名6月龄儿及72名8月龄婴儿免疫前、免疫后采用酶联免疫吸附试(ELISA)检测麻疹抗体IgG。结果 112名孕妇麻疹抗体阳性107例,阳性率95.5%,抗体滴度(GMRT)849.9;未达到保护水平有30例,占26.8%;6月龄和8月龄婴儿免疫成功率分别为98.0%、97.2%,免疫前麻疹抗体GMRT分别为4.1、1.1,差异均有显著性(均P<0.05),而免疫后麻疹抗体GMRT分别为782.0、976.5,差异无显著性(P>0.05)。结论 8月龄婴儿免疫效果稍好于6月龄婴儿,主要表现在免疫成功率方面,而免疫后抗体水平差异无显著性。

    【关键词】 妊娠;婴儿;麻疹疫苗;接种;抗体

    【Abstract】 Objective To get to know those pregnant women measles immune status and the infant’s measles vaccine immune effect.Methods To examine the measles antibody IgG of 112 pregnant women before parturition,50 6-month-old and 72 8-month-old infants before and after the immunity by ELISA.Results There are 107 women’s antibody show positive,the positive rate is 95.5% and GURT is 849.9. 30 women don’t come to the protective level,which takes over 26.89. The objective rate of immunity on 6-month-old and 8 month-old infants is 98% and 97.2% respectively.Before immunity, the measles antibody GURT of each group is 4.1 and 1.1. There is an obvious difference(P<0.05).While after immunity,the measles antibody GMRT is 782.0 and 976.5 respectively, which has no obvious difference (P>0.05).Conclusion The immune effect of 8-month old infants is better than that of 6-month old infants,which mainly make reflects on the immunity effective rate.After immunity,there are no obvious difference on antibody level. ......

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