摘要：目的：探讨抗结核药致药物性肝炎的发病规律与临床特点。方法：回顾性调查分析1999年1月至2004年6月以来本院住院肺结核患者在抗结核治疗中出现肝损害的临床相关因素以及误诊情况。结果：抗结核药致药物性肝炎与患者年龄、结核病分型、用药时间、初复治结核及合并其它疾病等相关，治疗预后较好。结论：认识影响抗痨致药物性肝炎有多种因素，定时检测肝功能，尽早发现、早诊断、早治疗，有利于抗痨疗程完成。

    关键词： 结核病； 药物性肝炎； 临床分析

    Analysis of 112 Cases of Drug-induced Hepatitis Caused by Anti-tubercular Drugs

    PANG zeng

    (Zhanjiang Center People's Hospital, Guangdong Zhanjiang 524037, China)

    Abstract： Objective: To investigate the clinical feature and etiology of drug-induced hepatitis caused by anti-tubercular (DIHAD) drugs. Method: Analysis of correlative factors and misdiagnoses of drug-induced hepatitis caused by anti-tubercular drugs for pulmonary tuberculosis during January 1999 to June 2004.Result: There is obvious correlations between of DIHAD and age, tuberculosis type, course of anti-tuberculosis, therapeutic history and exist of other diseases. The prognosis of DIHAD is good if it is treated in time. Conclusion: There are many factors correlated with DIHAD. In order to cure the tuberculosis safely, it is necessary to check the liver function regularly and find, diagnose, treat DIHAD as soon as possible. ......