大蒜_____大蒜；多糖；免疫性肝损伤；小鼠

大蒜多糖C对免疫性肝损伤小鼠血清及肝组织ALT、AST的影响

http://www.100md.com 《咸宁学院学报(医学版)》 2006年第1期

大蒜,,大蒜；多糖；免疫性肝损伤；小鼠,1材料和方法,2结果,3讨论,参考文献：

     摘要：目的观察大蒜多糖C对免疫性肝损伤小鼠血清和肝组织丙氨酸转氨酶(ALT)及天冬氨酸转氨酶(AST)的影响。方法建立卡介苗(BCG)加脂多糖(LPS)诱发的小鼠免疫性肝损伤模型，测定小鼠血清和肝组织ALT、AST。结果大蒜多糖C能使免疫性肝损伤小鼠血清ALT、AST活性显著降低，肝组织ALT、AST活性显著升高。结论大蒜多糖C对免疫性肝损伤具有保护性作用。

    关键词：大蒜；多糖；免疫性肝损伤；小鼠

    The Effects of the Allium Sativum L Polysaccharide C on

    ALT and AST in the Serum and Liver of

    Mice with Immunologic LiverinjuryZHAO Ji , ZHEN Min, BAO Cuiyu, et al

    (The Center Laboratory，Xianning College,Xianning Hubei 437100, China )

    ABSTRACT:Objective To study the effects of the allium sativum L polysaccharide C on the alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the serum and liver of mice with immunologic liverinjury. Methods Bacillus CalmetteGuein(BCG) plus lipopolysaccharide(LPS) was used to induce immunologic liverinjury model in mice. The activities of ALT and AST in serum and liver were measured. Results The allium sativum L polysaccharide C could significantly reduce the activities of ALT and AST in the serum but increase them in the liver of mice with immunologic liverinjury. Conclusion The allium sativum L polysaccharide C has protective effect on the immunologic liverinjury in mice. ......

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