奥美拉唑联合莫沙必利治疗反流性食管炎疗效观察
奥美拉唑,,奥美拉唑；莫沙必利；反流性食管炎；疗效,1材料与方法,2结果,3讨论
摘 要 目的：观察奥美拉唑联合莫沙必利治疗反流性食管炎的疗效。方法：将65例患者随机分为观察组(34例)和对照组(31例)，观察组：奥美拉唑 20 mg，晨服1次，莫沙必利每次5 mg，每日3次于餐前半小时口服；对照组：单用奥美拉唑20mg，晨服1次。两组治疗4周后均行内镜复查。结果：观察组临床有效率94.12%，内镜下有效率88.24%；对照组临床有效率7097%，内镜下有效率61.29%，两组比较差异有显著性(P<0.05)。结论：奥美拉唑联合莫沙必利治疗反流性食管炎比单独服用奥美拉唑具有更好的疗效。关键词 奥美拉唑；莫沙必利；反流性食管炎；疗效
The study of efficacy on reflux esophagitis of multitherapy with omeprazole and mosapride
ZHANG Xing, ZHOU He, SUN Honghui
(Affiliated Hospital of Guangdong College of Pharmacy, Guangzhou, Guangdong 510240)
Abstract Objective: observe the efficacy of multitherapy of omeprazole with mosapride on reflux esophagitis. Methods: 65 patients are randomly divided into study group (35 volunteers) and control group (31 volunteers). Two groups are treated with different therapies, for the study group, omeprazole 20 mg per day A. M., combined with mosapride 5 mg t.i.d. 30 minutes a.c.; while for the control group, monotherapy with omeprazole omeprazole 20 mg per day A. M.. Both the groups were arranged for endoscope examination. Results: the clinic effective rate of the study group was 94.12% with the effective rate under endoscope of 88.24%; while the clinic effective rate of the control group was 70.79% with the effective rate under endoscope of 61.29%. The difference of the efficacy between the two groups are significant statistically (P<0.05). Conclusions: The efficacy of multitherapy of omeprazole with mosapride on reflux esophagitis was better than that of monotherapy of omeprazole. ......
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