解毒利肺口服液质量控制方法研究
解毒利肺口服液,,解毒利肺口服液;TLC;HPLC;绿原酸,1仪器与试剂,2TLC鉴别,绿原酸含量测定,参考文献
摘 要 目的: 建立解毒利肺口服液质量控制方法。方法:采用薄层色谱法对金银花、黄芩和连翘有效成分进行鉴别。采用大孔树脂柱分离沉淀法分离绿原酸,用HPLC法测定含量。结果:TLC 鉴别的方法专属性较好,大孔树脂柱分离沉淀法可有效去除杂质,加样回收率96.68%, 精密度RSD 1.94% 。关键词 解毒利肺口服液;TLC;HPLC;绿原酸
Study on the quality control of Jiedu Lifei oral suspension
HAN Liping,SHI Shide,DENG Hai,ZHANG Weiling
(Department of Pharmacy,Guangzhou General Hospital of Guangzhou Military Command, Guangzhou,Guangdong 510010)
Abstract Objective: establishes the method for quality control of Jiedu Lifei Oral Suspension. Methods: assaying the active constituents of flos lonicerae, radix scutellariae, and fructus forsythiae; separating chlorogenic acid with macroporous resin column, and assaying the content with HPLC. Conclusions: the TLC method is more reliable and separation and precipitation with macroporous resin column can eliminate impurities effectively with a recovery rate of 96.68% and RSD of 1.94%.
Key words Jiedu Qingfei Oral suspension; TLC; HPLC; chlorogenic acid
解毒利肺口服液是根据治疗非典型性肺炎的医疗实践总结出来的中药处方研制的中药制剂 ......
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