【摘要】 目的 比较分析MRI与核素骨扫描在椎体骨转移诊断方面的敏感性、特异性。方法 60例(其中肺癌30例、前列腺癌15例、乳腺癌15例)疑椎体骨转移瘤患者，分别行全身核素骨扫描和脊柱MRI检查，比较两种方法对骨转移显示情况。结果 经病理或随访确诊为椎骨转移瘤50例。以受累椎体个数为统计单位，在脊柱范围内，共150个椎体确诊为转移；MRI诊断正确145个病灶，假阴性5个，无假阳性，其诊断敏感性为96.7%，特异性为100%；核素骨扫描诊断正确123个病灶，假阴性27个，假阳性7个，敏感性为82.0%，特异性84.6%。结论 在显示骨转移瘤方面，MRI较核素骨扫描具有更高的敏感性、特异性。

    【关键词】 脊柱；肿瘤转移；磁共振成像；核素骨扫描

    Evaluation of whole-body bone scanning and MR imaging in the detection of centrum metastasis

    TAN Ye-ying,TIAN Jia-he.Department of Nuclear Medicine,General Hospital of PLA,Beijing 100853,China

    【Abstract】 Objective To evaluate the ability of whole-body bone scanning(WBS)and MRI in the detection of centrum metastases of cancer and to compare their sensitivity,specificity.Methods 60 patients with cancer(lung 30,prostate 15,galactophore 15)were imaged with WBS and MRI.All the cases were proved by histopathology.The author compared the demonstration of centrum metastases with the two imaging modalities.Results In the centrum region,50 of the 60 patients with cancer were proved to have centrum metastases.Taking the total lesions as the samples,150 lesions were demonstrated as metastatic lesions.In MR imaging,true positive lesions were 145,false negative lesions were 5,false positive lesion were 0,the diagnostic sensitivity was 96.7%,the diagnostic specificity was 100%.In centrum scintigraphy,true positive lesions were 123,false negative lesions were 27,and false positive lesions were 7,the diagnostic sensitivity was 82.0%,the diagnostic specificity was 84.6%.Conclusion In diagnosing centrum metastases,MRI is more sensitive and correct than WBS. ......