针刺原位诱导阿尔茨海默病海马内源性神经干细胞的思考
神经干细胞,,]阿尔茨海默病;,神经干细胞;,针刺疗法,1AD的神经干细胞修复策略,2AD的神经干细胞修复研究思路,3神经干细胞修复研究的针刺
[摘要]回顾国内外有关阿尔茨海默病(Alzheimer disease, AD)与神经干细胞(neural stem cell, NSC)关系的文献,结合针刺治疗AD的实验研究成果,提出针刺原位诱导AD海马内源性NSC的增殖分化,可能是针刺治疗AD的作用机制,为进一步研究针刺治疗AD提供了新的思路和方向。[关键词]阿尔茨海默病; 神经干细胞; 针刺疗法
Pondering insitu induction of endogenous neural stem cells in hippocampus of rats with Alzheimer disease by acupuncture
TANG Yong, YIN HaiYan, ZENG Fang, YU ShuGuang
(Institute of Biomedical Engineering, West China Center of Medical Science, Sichuan University, Chengdu, Sichuan Province 610041, China; Department of Experimental Acupuncture, Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province 610075, China)
ABSTRACT Analysis of domestic and overseas literature on the relationship between Alzheimer disease (AD) and neural stem cells (NSC) shows that inducing the proliferation and differentiation of hippocampal endogenous NSC insitu by acupuncture is probably the mechanism of acupuncture therapy in treating AD, and that it may further improve the method for the research on AD.
KEY WORDS Alzheimer disease; neural stem cell; acupuncture therapy ......
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