Constant infusion of propofol in diffeª²rent induction modes for total intravenous anesthesia

    DING Qian, CHAI Wei, ZHAO Hui, YANG Yongª²Hui, ZHANG Guiª²He

    Department of Anesthesiology, Tangdu Hospital, Fourth Military Medical University, Xi¡¯an 710038,China

    ¡¾Abstract¡¿ AIM: To observe the hemodynamic changes and palinesthesia in constant infusion of propofol in different induction modes for total intravenous anesthesia (TIVA), and to investigate if the hemodynamic changes and palinesthesia are stable in general anesthesia and find out the best way of induction. METHODS: Sixty operated patients who were anesthetized by constant infusion of propofol according to the 9ª²7ª²5 strategy, were randomly divided into 3 groups: 1 min induction (group A), 2 min induction (group B) and 4 min induction (group C). Blood pressure (BP), heart rate (HR), pulse oxygen saturation (SpO2) and bispectral index (BIS) were monitored during the whole process of anesthesia. RESULTS: All groups induced and maintained with constant infusion of propofol got a satisfied general anesthesia. BP and BIS among groups had a significant difference during anesthesia induction(P<0.05). BP and BIS changed steadily in group C. Hemodynamic changes, SpO2 and BIS had no significant difference among groups during anesthesia maintenance(P>0.05). All the patients came around quickly and steadily (P>0.05). CONCLUSION: Constant infusion of propofol for TIVA could realize induction and maintenance, with quick and steady palinesthesia. Fourª²minute induction with constant infusion of propofol made hemodynamics steady in induction. ......