【摘 要】 目的 :观察间断性使用鼻罩式气道双水平正压(Bi-Level positive airway pressure，BiPAP)通气在治疗慢性阻塞性肺病(COPD)急性发作致呼吸衰竭患者时的疗效。 方法: 48例入选患者随机分为例数相同的试验组和对照组，在常规性治疗相同的情况下，对试验组间断使用鼻罩式BiPAP通气(每日3次，每次3h)，对照组只予持续低流量给氧，连续治疗3天后观察两组病人临床症状改善状况及血气分析指标并进行统计学比较分析。 结果: 试验组病例症状、体征及血气分析主要指标的改善在治疗后均明显好于治疗前，且好于治疗后的对照组。 结论: 间断使用鼻罩式BiPAP通气是治疗COPD急性发作患者的一种有效的无创辅助通气方法。

    【关键词】 BiPAP通气;COPD急性发作;间断性

    Evaluation of the efficacy of the discontinuously and nasallyBiPAP ventilation therapy in COPD with acute outbreak

    【Abstract】 Objective: To observe the effect of the discontinuously、nasally bilevel positive airway pressure(BiPAP)ventilation actualized on the pa-tients with respiratory failure due to chronic obstructive pulmonary disease(COPD)with acute outbreak.Methods:The selected48patients were divided equally into test group and control one by randomization.While the conventional therapy were same in both groups ......