【摘要】 目的：评价奎硫平治疗精神分裂症的疗效和安全性。方法：以氯氮平作对比，奎硫平与氯氮平治疗门诊精神分裂症各30例，采用阳性症状与阴性症状量表(PANSS)、副反应量表(TESS)，在治疗前及治疗后第1、2、4、6、8周末分别评定疗效和不良反应。 结果：两组治疗前与治疗后PANSS总分和各项因子分比较差异均有显著性；奎硫平的显效率为73.3%，氯氮平显效率为77.8%；奎硫平的不良反应少于氯氮平。结论：奎硫平治疗精神分裂症疗效好，不良反应轻。

    【关键词 】 奎硫平；氯氮平；精神分裂症

    The clinical search of adopting quetiapine to treat outpatients of schizophernia

    PEI Xiao-long, WEN Wen, LI Yi

    (Yue bei Third People's Hospital of Guang Dong (Le Chang) 512200)

    【Abstract】 Objective：Evaluate the curative effectiveness and safety of adopting quetiapine to treat schizophrenia. Methods:Compared with clozapine, adopting quetiapine and clozapine to treat 30 Patients of schizophrenia respectively. Adopting PANSS and TESS, we evaluated the curative effectiveness and side effects before and after and after the weekends of the lst、2nd、4th、6th and 8th week.Results: There is notable difference between the two groups before and after the treatment, the curative effectiveness of quetiapine is 73.3%, and the curative effectiveness of clozapine is 77.8%, the side effects of quetiapine is less than that of clozapine.Conclusions: The curative effectiveness of adopting quetiapine to treat schizophrenia is good, and its side effects are slight. ...... 濠电姷顣介埀顒€鍟块埀顒€缍婇幃妯诲緞閹邦剛鐣洪梺闈浨归崕鏌ョ叕椤掆偓闇夐柨婵嗙墛绾爼鏌℃担闈涒偓婵嬬嵁瀹ュ洠鍋撻敐搴′簼缂併劍姘ㄧ槐鎺戔槈濮楀棙效缂備椒绶ゆ俊鍥箟閹绢喖閱囬柣鏂垮濡差垶姊洪崫鍕殶濠殿喚鏁稿☉鐢稿醇閺囩偠鎽曢梺闈涳紡閸曨厾鏆梻浣烘嚀閻°劑鎮ч弮鍌滅當闁告侗鍠楁慨婊堟煢濡警妲哥€殿喖娼￠弻锟犲磼濮橆厾銈紓浣介哺缁诲牆鐣烽敐澶樻晬婵犻潧妫楅獮瀣⒑閸濆嫬顏撮柛銊ф暬閿濈偤鏁冮崒姘鳖啇濠电姴锕ら幊搴ㄥ磻瀹ュ洠鍋撳▓鍨灍婵炲弶锕㈤獮鏍川婵犲倻绐為柡澶婄墐閺呮粓宕洪崒鐐寸厓闁靛濡囬惌搴㈢箾閺夋垶顥㈤柟顖氱У閹峰懎霉鐎ｎ亙澹曞┑鐘茬仛閹稿墽绮堟径鎰仯闁搞儺鍓﹀Λ鎴︽煕鐎ｅ墎绉€规洘鐟ч幏鐘绘嚑椤掍胶绉虫俊銈囧Х閸嬬偛煤濡亽鈧帡鎳滈悽纰樻灃闁诲函缍嗛崑鍛存偂濞嗘挻鐓熼柕濞垮劚椤忋倝鏌嶈閸撴氨鍒掓惔銊ユ瀬闁归棿鐒﹂崵鍥煙鐎电ǹ孝妞わ絽銈搁弻宥夊Ψ閿斿墽鐣洪梺鎼炲妸閸旀垿宕归幆褉鍫柛鎰╁妽閺嬪墽绱撻崒姘殲闁搞劌娼℃俊瀛樺緞閹邦剛浼嬪┑鐘绘涧楗挳宕箛娑欌拻闁稿被鍊曢弸鏃堟煃瑜滈崜銊╁箯閿燂拷


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