食管癌化疗患者生活质量评价133例
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钱 勇, 张从军, 陈振东
生活质量;食管肿瘤;EORTCQLQ;问卷;化疗,钱勇,张从军,陈振东,通讯作者:,电话：, 传真：,Assessmentoflifequali
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钱勇, 张从军, 陈振东, 安徽医科大学第一附属医院肿瘤内科 安徽省合肥市 230022安徽省科技厅2005年度重点资助项目, No. 05021002
通讯作者: 陈振东, 230022, 安徽省合肥市, 安徽医科大学第一附属医院肿瘤内科. chenzhendong@csco.org.cn
电话：0551-3620262 传真：0551-3620262
Assessment of life quality of esophageal cancer patients received chemotherapy
Yong Qian, Cong-Jun Zhang, Zhen-Dong Chen
Yong Qian, Cong-Jun Zhang, Zhen-Dong Chen, Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Supported by the Key Foundation of Science and Technology Department of Anhui Province during the Year 2005, No. No. 05021002
Correspondence to: Professor Zhen-Dong Chen, Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China. chenzhendong@csco.org.cn
Received: 2006-04-25 Accepted: 2006-05-11
Abstract
AIM: To evaluate the quality of life (QOL) in esophageal cancer patients and investigate the differences in QOL with respect to social and medical characteristics.
METHODS: Structured questionnaires (EORTC QLQ-C30 and QLQ-OES18) were used for data collection in 133 consecutive esophageal cancer patients. The t-test and one-way analysis of variance (ANOVA) were used to compare the differences in QOL at a 5% significance level.
RESULTS: Without regard to the effectiveness of chemotherapy, almost all the patients’QOL declined slightly at the end of the 1st week, but returned to the baseline level at the end of the 4th wk. The scores for physical function, role function, cognitive function, social function and overall health status were remarkably higher in the patient less than 55 years old (P < 0.05). The scores of symptoms were increased with the ages of patients, and fatigue, insomnia and appetite loss made sense statistically. More civilized patients had higher scores of social function and lower score of financial difficulties (P < 0 ......
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