特异性免疫治疗母婴传播所致慢性乙型肝炎23例
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郑鹏远, 娄海山, 王永红, 唐芙爱, 白 蓉,
慢性乙型肝炎;树突状细胞;乙肝免疫球蛋白;免疫疗法郑鹏远,娄海山,王永红,唐芙爱,白蓉,司方明,白经修,琚新.特异性免疫治疗母婴传播所致慢性乙型肝炎23例. 世界华人消化杂志2006;14
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郑鹏远, 唐芙爱, 司方明, 白经修, 郑州大学第二附属医院消化科 河南省郑州市 450014
娄海山, 王永红, 琚新, 许昌市人民医院感染科 河南省许昌市 461000
白蓉, 郑州大学第五附属医院内科 河南省郑州市 450052河南省卫生厅医学创新人才工程项目, No. 2004-45
河南省科技厅科技攻关项目, No. 0324410006
通讯作者: 郑鹏远, 450014, 河南省郑州市经八路2号, 郑州大学第二附属医院消化科. medp7123@yahoo.com
电话: 0371-65261035
收稿日期: 2006-04-28 接受日期: 2006-05-17
Potential effect of specific immunotherapy on chronic hepatitis B of vertical maternal-fetal transmission: an analysis of 23 cases
Peng-Yuan Zheng, Hai-Shan Lou, Yong-Hong Wang, Fu-Ai Tang, Rong Bai, Fang-Ming Si, Jing-Xiu Bai, Xin Ju
Peng-Yuan Zheng, Fu-Ai Tang, Fang-Ming Si, Jing-Xiu Bai, Department of Gastroenterology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, Henan Province, China
Hai-Shan Lou, Yong-Hong Wang, Xin Ju, Department of Infectious Diseases, Xuchang People’s Hospital, Xuchang 461000, Henan Province, China
Rong Bai, Department of Internal Medicine, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Supported by Medical Innovation Talent Program of Health Department, Henan Province, No. 2004-45, and the Key Item of Science and Technology Department of Henan Province, No. 0324410006
Correspondence to: Peng-Yuan Zheng, Department of Gastroenterology, the Second Affiliated Hospital of Zhengzhou University, 2 Jingba Road, Zhengzhou 450014, Henan Province, China. medp7123@yahoo.com
Received: 2006-04-28 Accepted: 2006-05-17
Abstract
AIM:To study the efficacy of specific immuno-therapy in the treatment of patients with chronic hepatitis B (CHB) of vertical maternal-fetal transmission.
METHODS:HBsAg vaccine-loaded dendritic cells (DC, 106) and HBIg (200 U) were injected respectively into 23 patients with CHB of vertical transmission. Six months were considered as one course, and there were two courses in total ......
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