乙型肝炎病毒家族聚集性感染者的基因型和基因变异特征分析
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刘成永, 高玉金, 侯远沛, 杨友国, 钱秀梅,
乙型肝炎病毒;基因型;变异;家族聚集感染刘成永,高玉金,侯远沛,杨友国,钱秀梅,孙庆,宋丽.乙型肝炎病毒家族聚集性感染者的基因型和基因变异特征分析. 世界华人消化杂志2006;14(18)
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刘成永, 侯远沛, 钱秀梅, 孙庆, 宋丽, 江苏省徐州市传染病医院检验科 江苏省徐州市 221004
高玉金, 杨友国, 江苏省徐州市传染病医院肝病科 江苏省徐州市 221004
通讯作者: 刘成永, 221004, 江苏省徐州市, 传染病医院检验科. liucy0913@126.com
电话: 0516-83668716 传真: 0516-83668717
收稿日期: 2006-04-15 接受日期: 2006-05-29
Analysis of hepatitis B virus genotypes and gene mutation in patients with family infection
Cheng-Yong Liu, Yu-Jin Gao, Yuan-Pei Hou, You-Guo Yang, Xiu-Mei Qian, Qing Sun, Li Song
Cheng-Yong Liu, Yuan-Pei Hou, Xiu-Mei Qian, Qing Sun, Li Song, Clinical Laboratory of Xuzhou Infectious Disease Hospital, Xuzhou 221004, Jiangsu Province, China
Yu-Jin Gao, You-Guo Yang, Department of Hepatology, Xuzhou Infectious Disease Hospital, Xuzhou 221004, Jiangsu Province, China
Correspondence to: Cheng-Yong Liu, Clinical Laboratory of Xuzhou Infectious Disease Hospital, Xuzhou 221004, Jiangsu Province, China. liucy0913@126.com
Received: 2006-04-15 Accepted: 2006-05-29
Abstract
AIM:To investigate the genotypes and gene mutation of hepatitis B virus (HBV) in family infection.
METHODS:Eighty-four members from 27 families, whose internal genotypes were completely the same, were selected, including 29 cases of asymptomatic HBV carriers (ASC), 23 cases of chronic active hepatitis (CAH), 21 cases of liver cirrhosis (LC) and 11 cases of hepatocellular carcinoma (HCC) ......
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