摘要:目的 观察头孢哌酮/舒巴坦治疗急诊重症感染的有效性及安全性。 方法 对88例急诊重症感染患者，给予头孢哌酮/舒巴坦治疗，采用静脉滴入方式，每12h给药4.0g，观察其临床疗效及安全性。 结果 头孢哌酮/舒巴坦治疗急诊重症感染的有效率为81.8%，细菌清除率为83.8%，不良反应率为5.7%。 结论 急诊重症感染以革兰阴性菌为主，头孢哌酮/舒巴坦具有高效、安全的特点，可作为急诊重症感染的经验用药。

    关键词:头孢哌酮;舒巴坦;急诊;重症感染;疗效

    Clinical observation on the results in treatment of severe infections with cefoperazone sodium and snlqactam sodium.

    ZENG Qi，XING Bai.

    (Emergency Outpatient of Hainan Provincial Nongken Bureau Hospital，Haikou570311，Hainan，P.R.Chi-na)

    Abstract:Objective To observe the clinical efficacy and safety of cefoperazone/sulbactam in treatment of emergency severe in-fections. Methods A total of88emergency patients with severe infections were given cefoperazone/sulbactam4.0g/12h，iv drip and the clinical efficacy and safetywere observed. Results The clinical cure rates and bacterial clearance rates in the patients with emergency severe infections were81.8%and83.8%，while the adverse drug reactions rates were5.7%. Conclusion Gram-negative bacteria act as major pathogens in the emergency severe infections，cefoperazone/sulbactam is an effective and safe drug in treatment of emergent severe infections. ......