急性有机磷农药中毒阿托品用量探讨
急性有机磷农药;中毒;阿托品,,急性有机磷农药;中毒;阿托品,【摘要】,【关键词】,1资料与方法,2结果,3讨论,【参考文献】
【摘要】 目的 探讨急性有机磷农药中毒(AOPP)时,阿托品用量对疾病转归的影响。方法 将中度中毒以上患者分成中度中毒组、重度中毒组及濒死组,观察3组中阿托品首剂量、阿托品化量、阿托品总量、阿托品过量例数及死亡率。再将重度中毒组及濒死组中阿托品过量患者归为阿托品过量组、阿托品不过量者为阿托品适量组,比较两组中毒的时相发展、并发症及死亡率。结果 阿托品化量及阿托品总量濒死组>重度中毒组>中度中毒组(P<005)。阿托品过量组中的中间综合征(IMS)、中毒性心肌炎的发生率明显低于阿托品适量组 (P<005)。结论 AOPP时,中毒程度不同,阿托品的用量也不同,阿托品化量及首剂量也不同。维持阿托品化时易致阿托品过量,但轻度阿托品过量不会增加死亡率及并发症。【关键词】 急性有机磷农药;中毒;阿托品
【Abstract】 Objective To study the effect of atropine dosage on those patients that suffered from acute organophosphorus pesticide (AOPP)Methods Exploring the atropine's frist dosage,suitable dosage,and complication,mortality was observed by dividing these patiens into three groups:moderate intoxication,severe intoxication and the patients on the bring of deathResults The more amount of atropine was used,the more severe intoxication happened (P<005)The incident atropine(P<005)Conclusion For AOPP,the degree of atropine,it was easy to lead to overdose when moderate atropine was used persistently but slight overdose didn't increase the mortality and complication ......
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