摘 要 目的：总结绝经后子宫内膜癌的临床特点。方法：回顾性分析32例绝经后子宫内膜癌的临床资料。结果：绝经后子宫内膜癌以阴道出血为最突出表现，糖尿病是子宫内膜癌的高危因素，经阴道彩色多普勒超声检查是重要的检查手段，诊刮是术前确诊的主要方法。手术是最主要的治疗方法，次广泛子宫切除术可作为子宫内膜癌的基本术式。绝经后透明细胞癌、腺鳞癌等非子宫内膜样腺癌的比例明显升高，手术-病理分期较晚者多见，预后差，3年和5年生存率分别为67.8%和47.5%。结论：糖尿病是绝经后子宫内膜癌的高危因素，绝经后子宫内膜癌的发生与雌激素无关，手术-病理分期是绝经后子宫内膜癌重要的预后因素，绝经后子宫内膜癌的预后差。

     关键词 子宫内膜癌；绝经；预后

    Clinical Analysis of Endometrial Carcinoma in 32 Postmenopausal Patients

    Zhu Jiezhi,Jin Liping,Liu Xueling

    Department of obstetrics and gynecology, Heping Hospital of Changzhi Medical College

    Abstract Objective:To retrospectively analyze the clinical characteristics and outcomes of endometrial carcinoma(EC) in postmenopausal patients. Methods: Clinical data of 32 cases of postmenopausal EC were reviewed. Results: Irregular postmenopausal bleeding is the dominate symptom of postmenopausal EC, diabetes is the most important high-risk factor, transvaginal color Doppler flow image is a useful method for screening, and endometrial biopsy is the main diagnostic procedure. Extended hysterectomy is the standard surgery. The proportion of nonendometrioid carcinoma (undifferentiated, clear cell, uterine serous papillary, and squamous cell carcinoma) is higher in postmenopausal EC. The nonendometrioid tumors, compared to the endometrioid types, were more often high-stage tumors. The 3-and 5-year survival rate in postmenopausal EC was 67.8% and 47.5% respectively. Conclusions: Postmenopausal EC is less likely to be estrogen-related and has a poorly prognosis. ......