脑外伤；下呼吸道；院内感染；病原菌；药物敏感试验_

重度脑外伤院内下呼吸道感染病原菌分布及其耐药性监测

http://www.100md.com 《东南国防医药》 2004年第6期

脑外伤；下呼吸道；院内感染；病原菌；药物敏感试验,,]脑外伤；下呼吸道；院内感染；病原菌；药物敏感试验,[摘要],[关键词],1对象与方法,2

     [摘要]目的探讨重度脑外伤院内下呼吸道感染细菌谱及耐药情况。方法回顾1998年1月~2003年12月神经外科病房196例下呼吸道分泌物培养及药敏结果。结果重度脑外伤患者院内下呼吸道感染常见病原菌为鲍曼不动杆菌(37.2%)、金黄色葡萄球菌(31.6%)、肺炎克雷伯菌(27.0%)、铜绿假单胞菌(25.5%)及真菌；其中鲍曼不动杆菌、肺炎克雷伯菌及铜绿假单胞菌对亚胺培南西司他丁高度敏感，金黄色葡萄球菌对糖肽类万古霉素未发现耐药。结论重度脑外伤患者误吸、长期使用广谱抗生素及大剂量使用激素是院内下呼吸道感染的主要原因。

     [关键词]脑外伤；下呼吸道；院内感染；病原菌；药物敏感试验

    Distribution of the patterns of bacterial strains in lower respiratory tract infection in hospitalized patients with severe brain trauma and monitoring the durg resistance of bacterias

    NIE Sen, HE Haodi，ZHAO Chunming. Department of Respiratory Disease, the 98th Hospital of PLA, Huzhou 313000

    [Abstract]ObjectiveTo investigate the patterns of bacterial strains in lower respiratory tract infection in hospitalized patients with severe brain trauma and the drug resistance of bacterias.MethodsAnalyse retrospectively the results of the lower respiratory tract secretion cultivation and the drug sensitivity test of 196 cases in neurosurgery ward from January 1998 to December 2003.ResultsGramnegative bacillus found in most patients with sever brain trauma. The prevalences of strains in isolates of A. baumannii, S.aureus, K. pneumoniae, P. aeruginosa were 37.2%, 31.6%, 27.0% and 25.5% respectively. The drug sensitivity rates of Imipinem to A. baumannii, K. pneumoniae and P. aeruginosa were the highest, S.aureus had no drug resistance rate to Vancomycin.ConclusionsAspiration ......

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