输卵管妊娠保守性治疗后血β-HCG下降水平的临床分析
输卵管妊娠;保守性治疗;血β-HCG,,输卵管妊娠;保守性治疗;血β-HCG,1对象与方法,2结果,3讨论,【参考文献】
【摘要】 目的 探讨不同保守性方法治疗输卵管妊娠后血β-HCG下降的速度、幅度及其影响因素。方法 回顾性分析保守性治疗输卵管妊娠124例,其中药物治疗组36例(A组),保守性手术加术中输卵管局部注射甲氨蝶呤(MTX)50mg组60例(B组),单纯保守性手术组28例(C组),并与同期30例行输卵管切除术的患者对照(对照组)。治疗后定期监测血β-HCG水平并分析有关影响因素。结果 A组中32例血β-HCG<3000u/L者治疗成功,4例血β-HCG>3000u/L者均失败。B组60例均治愈。C组26例成功,2例发生持续性输卵管妊娠。B组术后血β-HCG降至正常时间明显短于A组和C组。结论 输卵管妊娠保守性治疗后监测血β-HCG极为重要。手术中采用输卵管注射MTX可加快术后血β-HCG下降速度。【关键词】 输卵管妊娠;保守性治疗;血β-HCG
Clinical analysis on serum βHCG level in tubal pregnancy treated conservatively
JIANG Shao-qing,CHEN Feng-hua.The Peoples Hospital,Huadu District,Guangzhou 510800,China
【Abstract】 Objective To analyze the reductive rate, extent and influential factors of serum β-HCG levels after different conservative treatment for tubal pregnancy.Methods A retrospective study on 124 cases received conservative treatment for tubal pregnancy, including 36 cases treated with drugs alone (Group A),60 women with conservative surgery plus fallopian local injection of MTX 50mg (Group B),and 28 treated with conservative surgery alone (Group C). The levels of β-HCG were surveiled every three days after conservative treatment until returned to normal.Results 32 cases with β-HCG<3000u/L in Group A cured completely, except for 4 women with B-HCG>3000u/L. All 60 women of Group B and 26 of 28 women of Group C healed also,2 cases in Group C developed persistent ectopic pregnancy.The mean time for decline of β-HCG to normal levels was significantly shorter in Group B than in Group C and Group A.Conclusion Conservative surveillance of β-HCG level after conservative treatment is very important.Fallopian local injection of MTX during conservative surgery may accelerate the decline of postoperative β-HCG concentration. ......
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