人工；心脏起搏器；ATⅢ；FPA；PF4；βTG_

不同起搏模式对ATⅢ、FPA、PF4和βTG的影响及意义

http://www.100md.com 《河北医药》 2006年第5期

人工；心脏起搏器；ATⅢ；FPA；PF4；βTG,,人工；心脏起搏器；ATⅢ；FPA；PF4；βTG,1资料与方法,2结果,3讨

     【摘要】目的探讨永久心脏起搏早期及不同起搏模式对血浆抗凝血酶Ⅲ(ATⅢ)、纤维蛋白肽A(FPA)、血小板因子4(PF4)和血小板β球蛋白(βTG)的影响及意义。方法对30例植入永久心脏起搏器患者，根据起搏模式分为两组，其中心室按需(VVI)型组(V组)15例，双腔(DDD)起搏器组(D组)15例。测定其术前当天、术后7 d的ATⅢ、FPA、PF4、βTG。结果术后ATⅢ较术前明显降低，FPA较术前明显升高。PF4、βTG较术前升高且V组升高较D组明显。结论本研究说明心脏起搏器植入后(1)凝血系统失衡，抗凝降低，凝血增强；(2)血小板活性增强，单腔起搏较双腔起搏更明显。

    【关键词】人工；心脏起搏器；ATⅢ；FPA；PF4；βTG

    Change and significance of AT3,FPA,PF4 and βTG in different model permanentpacing patients ZHANG Qinting,HU Meiqin,ZHAO Shumei.Department of Cardiolology.Rehabitation Hospital of Veterans,Hebei,Xingtai 054000

    【Abstract】 Objective To investigate the effect of different model of permanent pace maker on AT3,FPA,PF4 and βTG at early period.Methods 30 permanent cardiac pacing patients were divided into two groups according to pacing model.There were 15 patients with VVI pacemaker (group V) and 15 patients with DDD pacemaker (group D).The levels of AT3,FPA,PF4 and βTG in 30 patients were detected before and 7 day after pacing.Results After pacing AT3 decreased,however,FPA increased.PF4 and βTG obviously increased in group V,as compared with those in group D.Conclusion (1) There is coagulation disorder in pacing patient.The activity of anticoagulant is decreased and coagulation is increased.(2) Platelet activation is increased after pacing and the WI model is more obvious than DDD model. ......

百拇医药网 http://www.100md.com/html/DirDu/2006/07/03/02/43/07.htm

您现在查看是摘要页，全文长 5866 字符。