【摘要】 目的 考察多肽复合冲剂对帕金森病(PD)临床症状的控制和改善。方法 选择PD病人50例，随机分为治疗组和对照组，对照组采用美多巴治疗，治疗组在此基础上加用多肽复合冲剂。分别比较两组治疗前后Hoehn-Yahr(H-Y)分级和改良Webster量表评分变化及两组间的疗效差异。结果 与对照组比较，治疗组的H-Y分级和改良Webster量表评分明显减少(P<0.05)，总有效率明显提高(P<0.05)。结论 在使用美多巴的基础上加用多肽复合冲剂治疗PD，可明显增强疗效。

    【关键词】 多肽复合冲剂；帕金森病；治疗；神经生长因子；神经节苷脂；临床疗效

    Clinical efficacy of Duotai Fuhe Chongji for treating Parkinson’s disease

    QIAN Shi-ming，DONG Wang-Chao.

    Nanjing University of Traditional Chinese Medicine，Nanjing 210029，China

    【Abstract】 Objective To observe the clinical efficacy of Duotai Fuhe Chongji (DFCh) for patients with parkinson’s disease(PD).Methods 50 patients with PD were divided randomly into two groups：treatment group and control group. The former was administered Madopar，while the latter was given Madopar and DFCh. The Hoehn-Yahr(H-Y) score and modified Webster were measured before and after treatment in each group.Results The gradings by H-Y score and modified Webster were significantly reduced and the total effective rate was noticeably increased in treatment group when compared with control group (P<0.05).Conclusion DFCh combined with Madopar can obviously enhance improvement of clinical symptoms of patients with PD. ......