【摘要】 目的 描述黑龙江省女性乳头抽吸液的采集情况，分析影响乳头抽吸液采集的因素，为进一步研究其作为乳腺癌诊断方法的可行性提供依据。 方法 经医生和受试者同意，采集乳头抽吸液并进行问卷调查，采用logistic回归法分析影响乳头抽吸液采集的因素。 结果 乳头抽吸液的成功采集率为33.9%。乳腺癌患者与乳腺良性疾病患者及健康妇女乳头抽吸液的采集率无统计学差别(P=0.452)。单因素分析表明:①年龄在30～50岁之间;②初潮年龄早;③经产妇哺乳时间≥12个月;④湿性耵聍;⑤高脂肪饮食;⑥月经规律的妇女比绝经的妇女，乳头抽吸液成功采集率高(P<0.05)。以年龄和身高体重指数作为混杂因素，多因素分析结果提示，初潮年龄早、哺乳时间长和湿性耳耵聍易采集到乳头抽吸液。 结论 黑龙江省女性乳头抽吸液的成功采集率较低，样品的成功采集与受试者的年龄、月经史、哺乳史等因素有关。

     【关键词】 乳腺肿瘤;抽吸;危险因素

    Study on the nipple aspirate fluid collection and related factors

    GAO Dan-ning ，XUE Ying-wei ，ZHANG Qiu-juan ，LI Hui ，LI Kang，WANG Bin-you ，PANG Da ，ZHAO Ya-shuang .

    1.School of Public Health，Harbin Medical University，Harbin 150081，China;

    2.Third Clinical Hospital of Harbin Medical University(Tumour Hospital of Heilongjiang)，Harbin 150040，Chi-na;

    3.Health Care and Prevention Hospital of Harbin Medical University，Harbin 150001，China

    【Abstract】 Objective To describe the situation of nipple aspirate fluid(NAF)in women in Hei-longjiang，and to explore the feasibility of obtaining NAF in China in order to provide basis for further research on the diagnosis of breast cancer.Methods NAF of non-lactating women were collected and surveyed with questionnaire after consenting of physician and study subjects.Univariate and multivariate logistic regression analysis were used to analyse the factors associated with obtaining NAF.Results NAF was produced in detectable amounts by33.9%of all the subjects.No significant statistical differ-ent successfully obtained among healthy women ......