脂肪肝引起糖代谢异常的临床研究
甘油三酯;脂肪肝;糖代谢异常,,甘油三酯;脂肪肝;糖代谢异常,1对象与方法,2结果,3讨论,【参考文献】
【摘要】 目的 探讨脂肪肝与糖代谢异常之间的关系。方法 (1)将234例受检者按照B超诊断结果分为脂肪肝组和非脂肪肝组,检测血脂、血糖和胰岛素含量,计算胰岛素抵抗指数(HOMA-IR);(2)将脂肪肝组中无糖代谢异常的受检者分为治疗组(服用贝特类降脂药物)和非治疗组,连续观察3年,检测其血脂、血糖和胰岛素含量,计算HOMA-IR。结果 脂肪肝组糖代谢异常的发生率及血甘油三酯(TG)、血糖、胰岛素含量及HOMA-IR均显著高于非脂肪肝组(P<0.05~0.001);脂肪肝治疗组糖代谢异常的发生率及血TG、血糖、胰岛素含量及HOMA-IR较治疗前显著降低(P<0.05~0.001),非治疗组血TG、血糖、胰岛素含量及HOMA-IR较3年前显著升高(P<0.05~0.001)。结论 脂肪肝与糖代谢异常关系密切,积极治疗脂肪肝有助于推迟或防止糖代谢异常的发生。【关键词】 甘油三酯;脂肪肝;糖代谢异常
【Abstract】 Objective To explore the relationship between fatty liver and glycometabolism abnormality.Methods (1)According to diagnosis results by B ultrasound test,divided 234 cases into fatty liver group and non-fatty liver group,their blood fat、blood sugar and insulin were measured,the index of resisting insulin(HOMA-IR)were also calculated.(2)The patients of no glycometabolism abnormality in fatty liver group We are divided treatment group(take B decreasing lipid drugs)and no treatment group ......
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